Keynote Address : Wavelets and advanced biomedical imaging

Speaker: Professor Michael Unser
Biomedical Imaging Group
École Polytechnique Fédérale de Lausanne
Switzerland

Chair:

 

Abstract: Our purpose in this talk is to advocate the use of wavelets for advanced bioimaging. We start with a short tutorial on wavelet bases, emphasizing the fact that they provide a concise multiresolution representation of images and that they can be computed most efficiently. We then discuss a simple—but remarkably effective—image denoising procedure that essentially amounts to discarding small wavelet coefficients (soft-thresholding); we show that this type of algorithm is the solution of a variational problem that promotes “sparse” solutions. We believe that the underlying principle of wavelet regularization is a powerful concept that can be used advantageously in a variety of inverse image-reconstruction problems, including MRI and computed tomography.

We illustrate our point by presenting a novel wavelet-based deconvolution algorithm for 3D fluorescence microscopy, as well as some preliminary results for dynamic PET reconstruction. We will also discuss wavelet techniques for the analysis of functional MRI data and optical microscopy (extended depth of field)..

Biography: Michael Unser is Professor and Director of EPFL's Biomedical Imaging Group, Lausanne, Switzerland. His main research area is biomedical image processing. He has a strong interest in sampling theories, multiresolution algorithms, wavelets, and the use of splines for image processing. He has published over 150 journal papers on those topics, and is one of ISI’s Highly Cited authors in Engineering (http://isihighlycited.com).

From 1985 to 1997, he was with the Biomedical Engineering and Instrumentation Program, National Institutes of Health, Bethesda USA, conducting research on bioimaging and heading the Image Processing Group.

Dr. Unser is a fellow of the IEEE and the recipient of three Best Paper Awards from the IEEE Signal Processing Society. He was recently elected to the Swiss Academy of Engineering Sciences.

 

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